TKA + rifle. Not because it is supposed to rule pvp but because it is damn fun. You get two completely different playing styles. You can hang back and play sniper support or you can rush in and dish it out hand to hand. The defensive bonuses stack really well too. It also allows you to fight in groups if you don't happen to have buffs. Just stay out of the fight and snipe. I use 360+ vbrandy and when stacked you can spam rifle specials all day (same with using a VK but have to watch action a little). I know self buffing would be nice but if you want a pure fighter it is pointless. Atkm with self buffs if just a tkm with buffs. A tkm with someone elses buffs is a tkm with a crap load of other defenses

But this is just play style I guess.
I am a big fan of combining ranged with melee to round a character out. I find it completely poinltess to put away my melee vk to be able to whip out another melee weapon to...uh... melee with it. There are several points left over too so you can dabble here and there or min/max stack some more. The concept of tkm/rifleman is one of high offense/modest defense. I prefer to dish out the damage over dodging around like a little pransing fairy.
I was building a little fencer in it too get more defense bonuses but am holding off on that awaiting the combat ballances to see what goes where and what doesn't stack and what not (say what?). It comes down to one thing: Rifleman is fun, TKM is fun so that is what I went back too (started out as a rifleman when I started). I tried pistol but didn't like it due to pistol sucking the big lemon in it's current state. Carbine was actually rather fun but a friend is going carbine and we all like to be something different (funny thing to mention is that carbine has a very high action cost and you need to be buffed and rifle has a very high mind cost and you need to be buffed...but seeing howanyone always self-buff mind anyway and you need a doc to buff action and substats unless using food/spice therebyelimiting precious mind buffs...I find using rifle easier than carbine, even with the mind drain. Hope that makes sense).
One nice thing about spending a few points in pistol to boost defenses is that you can pick up smuggler and be able to slice all those containers you find in caves and bases. Would be nice to get a little extra loot. Did it once and still have some pistol trained. I might keep that option open when combat ballances come in. I have a feeling many profession trees are going to be mixed up a little so no point wasting all my time now.
Another thing I seriously contemplated was tka/commando. Other professions needing unarmed as a prereq make it easy to dive into tka because you are spending the points anyway. You may not have insane defenses but there is something fun about pulling out the most powerful weapons in the game from time to time. When the GCW is evolved into something more spectacular commando's will really find their niche.
I have played around with the points a lot (cause I find that fun for some sick reason) and the things that tempted me were of the following three:
1) TKM/ranged weapon- to be able to play both sides of the fence and have good defenses to compliment TKM.
2) TKM/Commando- Big punches and Big weapons.
3) TKM/CH- Very common and I had fun at first but discovered that pets held me back and slowed me down so dropped it. Before dropping it though I seriously considered TKM/ Ranger tracking (possible traps too for a kick)/CH. This sounds really fun imo because you get tracking skills (trapping if taken) and still have enough into CH to whip out a serious tank (BE pet of course) plus it fits the wholetough ranger with pet theme (rifleman works well in the concept too and very popular with CH...hunter with gun theme). I still think this would be a fun option if I wasn't going pure fighter.
As for your extra points...MEDIC. I can't believe you left that open as an option. The way this game is, every character doesn't have 250 points when starting. You have 235 freebies cause medic is the first thing you take. Hell even the medic stat template is closest to what you will end up with anyway (mind, mind, mind and a little in other stats).
Sinumbra (Flurry),
Officer at large.